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GRM5 Rabbit mAb[75M2]Cat NO.: A56271

Western blot(SDS PAGE) analysis of extracts from Mouse brain tissue lysate.Using GRM5 Rabbit mAb IgG [75M2] at dilution of 1:1000 incubated at 4℃ over night.

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Product information

Protein names :GRM5,GPRC1E,MGLUR5,GRM5_HUMAN,Metabotropic glutamate receptor 5

UniProtID :P41594

MASS(da) :132,469

MW(kDa) :150kDa

Form :Liquid

Purification :Protein A purification

Host :Rabbit

Isotype :IgG

sensitivity :Endogenous

Reactivity :Mouse,Rat

  • ApplicationDilution
  • 免疫印迹(WB)1:1000-2000
  • The optimal dilutions should be determined by the end user

Specificity :Antibody is produced by immunizing animals with a synthetic peptide of Mouse GRM5.

Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected :Mouse brain tissue lysate

Function : G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity..

Subcellular locationi :Cell membrane,Multi-pass membrane protein.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.