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Western blot(SDS PAGE) analysis of extracts from Rat brain tissue lysate.Using ORP1 Rabbit mAb IgG [637N] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :OSBPL1A,ORP1,OSBP8,OSBPL1,OSBPL1B,OSBL1_HUMAN,Oxysterol-binding protein-related protein 1
UniProtID :Q9BXW6
MASS(da) :108,470
MW(kDa) :50kDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human,Mouse,Rat
Specificity :Antibody is produced by immunizing animals with a synthetic peptide of human ORP1.
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :Rat brain tissue lysate
Function : Binds phospholipids,exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A (PubMed:16176980). Binds 25-hydroxycholesterol and cholesterol (PubMed:17428193)..
Subcellular locationi :Late endosome.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.