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PGC1 beta Rabbit mAb[854H]Cat NO.: A21940

Western blot(SDS PAGE) analysis of extracts from HeLa cells.Using PGC1 beta Rabbit mAb IgG [854H] at dilution of 1:1000 incubated at 4℃ over night.

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Product information

Protein names :PPARGC1B,PERC,PGC1,PGC1B,PPARGC1,PRGC2_HUMAN,Peroxisome proliferator-activated receptor gamma coactivator 1-beta

UniProtID :Q86YN6

MASS(da) :113,222

MW(kDa) :113kDa

Form :Liquid

Purification :Protein A purification

Host :Rabbit

Isotype :IgG

sensitivity :Endogenous

Reactivity :Human,Mouse,Rat

  • ApplicationDilution
  • 免疫印迹(WB)1:1000-2000
  • The optimal dilutions should be determined by the end user

Specificity :Antibody is produced by immunizing animals with a synthetic peptide of human PGC1 beta.

Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected :HeLa cells

Function : Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner..

Tissue specificity :Ubiquitous with higher expression in heart, brain and skeletal muscle..

Subcellular locationi :Nucleus.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.