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Western blot(SDS PAGE) analysis of extracts from Mouse brain tissue lysate.Using PLC gamma 1 (PLCG1) Rabbit mAb IgG [Q8IT] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :PLCG1,PLC1,PLCG1_HUMAN,1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
UniProtID :P19174
MASS(da) :148,532
MW(kDa) :149kDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human,Mouse,Rat
Specificity :Antibody is produced by immunizing animals with a synthetic peptide of human PLC gamma 1 (PLCG1).
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :Mouse brain tissue lysate
Function : Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, EGFR, FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity). Plays a role in actin reorganization and cell migration (PubMed:17229814)..
Subcellular locationi :Cell projection, lamellipodium. Cell projection, ruffle.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.