Serotonin transporter Rabbit mAb[6GXQ]Cat NO.: A58063

Protein names ：SLC6A4,HTT,SERT,SC6A4_HUMAN,Sodium-dependent serotonin transporter

UniProtID ：P31645

MASS(da) ：70,325

MW(kDa) ：75kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000,
• 免疫荧光(ICC/IF) 1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide of human Serotonin transporter.

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：THP-1 cells

Function ： Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner..

Tissue specificity ：Expressed in platelets (at protein level)..

Subcellular locationi ：Cell membrane,Multi-pass membrane protein. Endomembrane system,Multi-pass membrane protein. Endosome membrane,Multi-pass membrane protein. Cell junction, synapse. Cell junction, focal adhesion.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.