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Western blot(SDS PAGE) analysis of extracts from HepG2 cells.Using Syntrophin alpha 1 Rabbit mAb IgG [BLUX] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :SNTA1,SNT1,SNTA1_HUMAN,Alpha-1-syntrophin
UniProtID :Q13424
MASS(da) :53,895
MW(kDa) :59kDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human,Mouse,Rat
Specificity :Antibody is produced by immunizing animals with a synthetic peptide of human Syntrophin alpha 1.
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :HepG2 cells
Function : Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5-bisphosphate (By similarity)..
Tissue specificity :High expression in skeletal muscle and heart. Low expression in brain, pancreas, liver, kidney and lung. Not detected in placenta.
Subcellular locationi :Cell membrane, sarcolemma,Peripheral membrane protein,Cytoplasmic side. Cell junction. Cytoplasm, cytoskeleton.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.