ADAM9 Rabbit mAb [P3IA]Cat NO.: A76302

Protein names ：ADAM9,KIAA0021,MCMP,MDC9,MLTNG,ADAM9_HUMAN,Disintegrin and metalloproteinase domain-containing protein 9

UniProtID ：Q13443

MASS(da) ：90,556

MW(kDa) ：100-115、75-80 kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide at the sequence of Human ADAM9

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：HeLa cells

Function ： Cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5. May mediate cell-cell, cell-matrix interactions and regulate the motility of cells via interactions with integrins.., [Isoform 2]: May act as alpha-secretase for amyloid precursor protein (APP)..

Tissue specificity ：Widely expressed. Expressed in chondrocytes. Isoform 2 is highly expressed in liver and heart..

Subcellular locationi ：[Isoform 1]: Cell membrane,Single-pass type I membrane protein.,[Isoform 2]: Secreted.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.