CD57 Mouse mAb[CXWJ]Cat NO.: A81204

Protein names ：B3GAT1,GLCATP,B3GA1_HUMAN,Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

UniProtID ：Q9P2W7

MASS(da) ：38,256

MW(kDa) ：38and100kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Mouse

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide of human CD57.

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：K-562 cells

Function ： Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group..

Tissue specificity ：Mainly expressed in the brain.

Subcellular locationi ：[Isoform 1]: Golgi apparatus membrane,Single-pass type II membrane protein. Secreted.,[Isoform 2]: Golgi apparatus membrane,Single-pass type II membrane protein. Endoplasmic reticulum membrane. Secreted.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.