CNBP Mouse mAb[1D2Z]Cat NO.: A63537

Protein names ：CNBP,RNF163,ZNF9,CNBP_HUMAN,CCHC-type zinc finger nucleic acid binding protein

UniProtID ：P62633

MASS(da) ：19,463

MW(kDa) ：19kda

Form ：Liquid

Purification ：Protein A purification

Host ：Mouse

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide of human CNBP.

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：HEK-293 cells

Function ： Single-stranded DNA-binding protein that preferentially binds to the sterol regulatory element (SRE) sequence 5'-GTGCGGTG-3', and thereby mediates transcriptional repression (PubMed:2562787). Has a role as transactivator of the Myc promoter (By similarity). Binds single-stranded RNA in a sequence-specific manner (By similarity).., [Isoform 1]: Binds G-rich elements in target mRNA coding sequences (PubMed:28329689). Prevents G-quadruplex structure formation in vitro, suggesting a role in supporting translation by resolving stable structures on mRNAs (PubMed:28329689).., [Isoform 2]: Binds to RNA.., [Isoform 4]: Binds to RNA.., [Isoform 5]: Binds to RNA.., [Isoform 6]: Binds to RNA.., [Isoform 8]: Binds to RNA..

Tissue specificity ：Expressed in the liver, kidney, spleen, testis, lung, muscle and adrenal glands..

Subcellular locationi ：Nucleus. Cytoplasm. Endoplasmic reticulum.,[Isoform 1]: Cytoplasm.,[Isoform 2]: Cytoplasm.,[Isoform 4]: Cytoplasm.,[Isoform 5]: Cytoplasm.,[Isoform 6]: Cytoplasm.,[Isoform 8]: Cytoplasm.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.