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Western blot(SDS PAGE) analysis of extracts from human plasma.Using HABP2 Mouse mAb IgG [384V] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :HABP2,HGFAL,PHBP,HABP2_HUMAN,Hyaluronan-binding protein 2 [Cleaved into: Hyaluronan-binding protein 2 50 kDa heavy chain,Hyaluronan-binding protein 2 50 kDa heavy chain alternate form,Hyaluronan-binding protein 2 27 kDa light chain,Hyaluronan-bindin
UniProtID :Q14520
MASS(da) :62,672
MW(kDa) :60,63kDa
Form :Liquid
Purification :Protein A purification
Host :Mouse
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human
Specificity :Antibody is produced by immunizing animals with a synthetic peptide of human HABP2.
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :human plasma
Function : Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro-urokinase) to the active two chain form. Activates coagulation factor VII (PubMed:8827452, PubMed:10754382, PubMed:11217080). May function as a tumor suppressor negatively regulating cell proliferation and cell migration (PubMed:26222560)..
Tissue specificity :Ubiquitously expressed..
Subcellular locationi :Secreted.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.