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KEL Mouse mAb[5TH0]Cat NO.: A95448

Western blot(SDS PAGE) analysis of extracts from human red blood cells.Using KEL Mouse mAb IgG [5TH0] at dilution of 1:1000 incubated at 4℃ over night.

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Product information

Protein names :KEL,KELL_HUMAN,Kell blood group glycoprotein

UniProtID :P23276

MASS(da) :82,824

MW(kDa) :93kDa

Form :Liquid

Purification :Protein A purification

Host :Mouse

Isotype :IgG

sensitivity :Endogenous

Reactivity :Human

  • ApplicationDilution
  • 免疫印迹(WB)1:1000-2000
  • The optimal dilutions should be determined by the end user

Specificity :Antibody is produced by immunizing animals with a synthetic peptide of human KEL.

Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected :human red blood cells

Function : Zinc endopeptidase with endothelin-3-converting enzyme activity. Cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3..

Tissue specificity :Expressed at high levels in erythrocytes and testis (in Sertoli cells), and, at lower levels, in skeletal muscle, tonsils (in follicular dendritic cells), lymph node, spleen and appendix (at protein level). Also expressed in many adult and fetal nonerythroid tissues, including brain, spleen, lymph nodes and bone marrow..

Subcellular locationi :Cell membrane,Single-pass type II membrane protein.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.