PDE4D Mouse mAb[52Q5]Cat NO.: A58301

Protein names ：PDE4D,DPDE3,PDE4D_HUMAN,cAMP-specific 3',5'-cyclic phosphodiesterase 4D

UniProtID ：Q08499

MASS(da) ：91,115

MW(kDa) ：91-120kDa,66-84kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Mouse

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide of human PDE4D.

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：A549 cells

Function ： Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes..

Tissue specificity ：Expressed in colonic epithelial cells (at protein level). Widespread,most abundant in skeletal muscle..,[Isoform 6]: Detected in brain..,[Isoform 8]: Detected in brain, placenta, lung and kidney..,[Isoform 7]: Detected in heart and skeletal muscle..

Subcellular locationi ：Apical cell membrane. Cytoplasm. Membrane. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.