RAB14 Mouse mAb[BGI7]Cat NO.: A47789

Protein names ：RAB14,RAB14_HUMAN,Ras-related protein Rab-14

UniProtID ：P61106

MASS(da) ：23,897

MW(kDa) ：24kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Mouse

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide of human RAB14.

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：HCT 116 cells

Function ： Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion..

Subcellular locationi ：Recycling endosome. Early endosome membrane,Lipid-anchor,Cytoplasmic side. Golgi apparatus membrane,Lipid-anchor,Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane,Lipid-anchor,Cytoplasmic side. Cytoplasmic vesicle, phagosome.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.