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Western blot(SDS PAGE) analysis of extracts from K-562 cells.Using STXBP2 Mouse mAb IgG [99NI] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :STXBP2,UNC18B,STXB2_HUMAN,Syntaxin-binding protein 2
UniProtID :Q15833
MASS(da) :66,453
MW(kDa) :66kDa
Form :Liquid
Purification :Protein A purification
Host :Mouse
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human,Mouse
Specificity :Antibody is produced by immunizing animals with a synthetic peptide of human STXBP2.
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :K-562 cells
Function : Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells..
Tissue specificity :Placenta, lung, liver, kidney and pancreas, as well as in peripheral blood lymphocytes.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.