PPP2R2B Mouse mAb[C4V1]Cat NO.: A82313

Protein names ：PPP2R2B,2ABB_HUMAN,Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

UniProtID ：Q00005

MASS(da) ：51,710

MW(kDa) ：52kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Mouse

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide of human PPP2R2B.

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：HepG2 cells

Function ： The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity (By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance (By similarity)..

Tissue specificity ：Brain.

Subcellular locationi ：[Isoform 1]: Cytoplasm. Cytoplasm, cytoskeleton. Membrane.,[Isoform 2]: Cytoplasm. Mitochondrion. Mitochondrion outer membrane.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.