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Western blot analysis of extracts from Human fetal heart tissue lyaste.using PDE4D Rabbit mAb [41R7] at dilution of 1:1000 incubated at 4℃ over night
Protein names :PDE4D,DPDE3,PDE4D_HUMAN,cAMP-specific 3',5'-cyclic phosphodiesterase 4D
UniProtID :Q08499
MASS(da) :91,115
MW(kDa) :91 kDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human
Specificity :Antibody is produced by immunizing animals with a synthetic peptide of Human PDE4D.
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :Human fetal heart tissue lyaste
Function : Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes..
Tissue specificity :Expressed in colonic epithelial cells (at protein level). Widespread,most abundant in skeletal muscle..,[Isoform 6]: Detected in brain..,[Isoform 8]: Detected in brain, placenta, lung and kidney..,[Isoform 7]: Detected in heart and skeletal muscle..
Subcellular locationi :Apical cell membrane. Cytoplasm. Membrane. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.