SH3GL2 Rabbit mAb [9ZS2]Cat NO.: A65288

Protein names ：SH3GL2,CNSA2,SH3D2A,SH3G2_HUMAN,Endophilin-A1

UniProtID ：Q99962

MASS(da) ：39,962

MW(kDa) ：40 kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide of Human SH3GL2.

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：Human cerebellum tissue lyaste

Function ： Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes..

Tissue specificity ：Brain, mostly in frontal cortex. Expressed at high level in fetal cerebellum.

Subcellular locationi ：Cytoplasm. Membrane,Peripheral membrane protein. Early endosome. Cell junction, synapse, presynapse.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.