LRMP Rabbit mAb [4181]Cat NO.: A44879

Protein names ：IRAG2,JAW1,LRMP,IRAG2_HUMAN,Inositol 1,4,5-triphosphate receptor associated 2 [Cleaved into: Processed inositol 1,4,5-triphosphate receptor associated 2]

UniProtID ：Q12912

MASS(da) ：62,122

MW(kDa) ：62 kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100,
• 免疫荧光(ICC/IF)1:100,
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide of Human LRMP.

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：Daudi cells lyastes

Function ： Plays a role in the delivery of peptides to major histocompatibility complex (MHC) class I molecules,this occurs in a transporter associated with antigen processing (TAP)-independent manner. May play a role in taste signal transduction via ITPR3. May play a role during fertilization in pronucleus congression and fusion. Plays a role in maintaining nuclear shape, maybe as a component of the LINC complex and through interaction with microtubules..

Tissue specificity ：Expressed at high levels in pre B-cells, mature B-cells and pre T-cells. Expressed at low levels in mature T-cells and plasma B-cells. Expressed in germinal center B-cells, splenic marginal zone cells and B-cell lymphomas. Expressed in neuronal cells in the cerebral cortex, epithelial cells in tonsil, adrenal glands, zymogen-producing cells in the stomach and epithelial cells in seminal vesicles..

Subcellular locationi ：[Processed inositol 1,4,5-triphosphate receptor associated 2]: Cytoplasm.,Endoplasmic reticulum membrane,Single-pass type IV membrane protein. Nucleus envelope. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Chromosome.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.