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Western blot analysis of extracts from Human placenta tissue lyaste.using HSD17B1 Rabbit mAb [7415] at dilution of 1:1000 incubated at 4℃ over night
Protein names :HSD17B1,E17KSR,EDH17B1,EDH17B2,EDHB17,SDR28C1,DHB1_HUMAN,17-beta-hydroxysteroid dehydrogenase type 1
UniProtID :P14061
MASS(da) :34,950
MW(kDa) :35 kDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human
Specificity :Antibody is produced by immunizing animals with a synthetic peptide of Human HSD17B1.
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :Human placenta tissue lyaste
Function : Favors the reduction of estrogens and androgens. Converts estrone (E1) to a more potent estrogen, 17beta-estradiol (E2) (PubMed:8994190). Also has 20-alpha-HSD activity. Uses preferentially NADH..
Subcellular locationi :Cytoplasm.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.