CD89 Rabbit mAb [3D1T]Cat NO.: A10870

Protein names ：FCAR,CD89,FCAR_HUMAN,Immunoglobulin alpha Fc receptor

UniProtID ：P24071

MASS(da) ：32,265

MW(kDa) ：32 kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100,
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide of Human CD89.

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：U937 cells lyastes

Function ： Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production..

Tissue specificity ：Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages,however only one isoform is expressed at alveolar macrophages surfaces..

Subcellular locationi ：[Isoform A.1]: Cell membrane,Single-pass type I membrane protein.,[Isoform A.2]: Cell membrane,Single-pass type I membrane protein.,[Isoform A.3]: Cell membrane,Single-pass type I membrane protein.,[Isoform B]: Secreted.,[Isoform B-delta-S2]: Secreted.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.