SRD5A2 Rabbit mAb [J88L]Cat NO.: A75751

Protein names ：SRD5A2,S5A2_HUMAN,3-oxo-5-alpha-steroid 4-dehydrogenase 2

UniProtID ：P31213

MASS(da) ：28,393

MW(kDa) ：28 kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide of Human SRD5A2.

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：LnCaP cells lyastes

Function ： Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology..

Tissue specificity ：Expressed in high levels in the prostate and many other androgen-sensitive tissues.

Subcellular locationi ：Microsome membrane,Multi-pass membrane protein. Endoplasmic reticulum membrane,Multi-pass membrane protein.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.