* 产品详情- */>
Western blot analysis of extracts from Human fetal muscle tissue lyaste.using SERCA1 ATPase Rabbit mAb [XSR2] at dilution of 1:1000 incubated at 4℃ over night
Protein names :ATP2A1,AT2A1_HUMAN,Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 -ATPase 1) ATPase)
UniProtID :O14983
MASS(da) :110,252
MW(kDa) :100 kDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human,Mouse,Rat
Specificity :Antibody is produced by immunizing animals with a synthetic peptide of Human SERCA1 ATPase.
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :Human fetal muscle tissue lyaste
Function : Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen (By similarity). Contributes to calcium sequestration involved in muscular excitation/contraction (PubMed:10914677)..
Tissue specificity :Skeletal muscle, fast twitch muscle (type II) fibers..
Subcellular locationi :Endoplasmic reticulum membrane,Multi-pass membrane protein. Sarcoplasmic reticulum membrane,Multi-pass membrane protein.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.