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Western blot analysis of extracts from A431 cells lyastes.using Nicalin Rabbit mAb [5NAR] at dilution of 1:1000 incubated at 4℃ over night
Protein names :NCLN,NCLN_HUMAN,Nicalin
UniProtID :Q969V3
MASS(da) :62,974
MW(kDa) :60 kDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human,Mouse,Rat
Specificity :Antibody is produced by immunizing animals with a synthetic peptide of Human Nicalin.
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :A431 cells lyastes
Function : Component of a ribosome-associated translocon complex involved in multi-pass membrane protein transport into the endoplasmic reticulum (ER) membrane and biogenesis (PubMed:32820719). May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning, via its interaction with NOMO (By similarity)..
Tissue specificity :Highly expressed in pancreas and skeletal muscle and, at lower levels, in heart..
Subcellular locationi :Endoplasmic reticulum membrane,Single-pass membrane protein.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.