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Western blot analysis of extracts from Human spleen tissue lyaste.using DcR1 Rabbit mAb [7ME9] at dilution of 1:1000 incubated at 4℃ over night
Protein names :TNFRSF10C,DCR1,LIT,TRAILR3,TRID,UNQ321/PRO366,TR10C_HUMAN,Tumor necrosis factor receptor superfamily member 10C
UniProtID :O14798
MASS(da) :27,407
MW(kDa) :27 kDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human
Specificity :Antibody is produced by immunizing animals with a synthetic peptide of Human DcR1.
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :Human spleen tissue lyaste
Function : Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
Tissue specificity :Higher expression in normal tissues than in tumor cell lines. Highly expressed in peripheral blood lymphocytes, spleen, skeletal muscle, placenta, lung and heart.
Subcellular locationi :Cell membrane,Lipid-anchor, GPI-anchor.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.