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Desmocollin 1 Rabbit mAb [49FB]Cat NO.: A80416

Western blot analysis of extracts from A375 cells lyastes.using Desmocollin 1 Rabbit mAb [49FB] at dilution of 1:1000 incubated at 4℃ over night

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Product information

Protein names :DSC1,CDHF1,DSC1_HUMAN,Desmocollin-1

UniProtID :Q08554

MASS(da) :99,987

MW(kDa) :100 kDa

Form :Liquid

Purification :Protein A purification

Host :Rabbit

Isotype :IgG

sensitivity :Endogenous

Reactivity :Human,Mouse,Rat

  • ApplicationDilution
  • 免疫印迹(WB)1:1000-2000
  • The optimal dilutions should be determined by the end user

Specificity :Antibody is produced by immunizing animals with a synthetic peptide of Human Desmocollin 1.

Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected :A375 cells lyastes

Function : Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. Linked to the keratinization of epithelial tissues.

Tissue specificity :Strongly expressed in epidermis, less in lymph node and tongue.

Subcellular locationi :Cell membrane,Single-pass type I membrane protein. Cell junction, desmosome.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.