EHD2 Rabbit mAb [EMF9]Cat NO.: A55169

Protein names ：EHD2,PAST2,EHD2_HUMAN,EH domain-containing protein 2

UniProtID ：Q9NZN4

MASS(da) ：61,161

MW(kDa) ：61 kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫荧光(ICC/IF)1:100,
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide of Human EHD2.

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：Fetal heart tissue lyaste

Function ： ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis (By similarity). Plays a role in membrane trafficking between the plasma membrane and endosomes (PubMed:17233914). Important for the internalization of GLUT4. Required for fusion of myoblasts to skeletal muscle myotubes. Required for normal translocation of FER1L5 to the plasma membrane (By similarity). Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by constraining caveolae at the cell membrane (PubMed:25588833)..

Tissue specificity ：Highly expressed in heart and moderately expressed in placenta, lung, and skeletal muscle..

Subcellular locationi ：Cell membrane,Peripheral membrane protein,Cytoplasmic side. Membrane, caveola,Peripheral membrane protein,Cytoplasmic side. Endosome membrane,Peripheral membrane protein,Cytoplasmic side. Cytoplasm, cytosol.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.