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Western blot analysis of extracts from Human serum tissue lyaste.using LBP Rabbit mAb [NW58] at dilution of 1:1000 incubated at 4℃ over night
Protein names :LBP,LBP_HUMAN,Lipopolysaccharide-binding protein
UniProtID :P18428
MASS(da) :53,384
MW(kDa) :60 kda
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human
Specificity :Antibody is produced by immunizing animals with a synthetic peptide of Human LBP.
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :Human serum tissue lyaste
Function : Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria (PubMed:7517398, PubMed:24120359). Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide (PubMed:7517398, PubMed:24120359)..
Tissue specificity :Detected in blood serum (at protein level)..
Subcellular locationi :Secreted. Cytoplasmic granule membrane.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.