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Western blot analysis of extracts from Human serum tissue lyaste.using C9 Rabbit mAb [0P62] at dilution of 1:1000 incubated at 4℃ over night
Protein names :C9,CO9_HUMAN,Complement component C9 [Cleaved into: Complement component C9a,Complement component C9b]
UniProtID :P02748
MASS(da) :63,173
MW(kDa) :72 kda
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human
Specificity :Antibody is produced by immunizing animals with a synthetic peptide of Human C9.
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :Human serum tissue lyaste
Function : Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells (PubMed:9634479, PubMed:9212048, PubMed:26841934). C9 is the pore-forming subunit of the MAC (PubMed:4055801, PubMed:26841934, PubMed:30111885)..
Tissue specificity :Plasma (at protein level)..
Subcellular locationi :Secreted. Target cell membrane,Multi-pass membrane protein.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.