OGG1 Rabbit mAb [8783]Cat NO.: A21515

Protein names ：OGG1,MMH,MUTM,OGH1,OGG1_HUMAN,N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase ,DNA- lyase ]

UniProtID ：O15527

MASS(da) ：38,782

MW(kDa) ：39KDa

Form ：Rabbit IgG

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide of Human OGG1.

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：HeLa cells lysate

Function ： DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.

Tissue specificity ：Ubiquitous.

Subcellular locationi ：Nucleus, nucleoplasm. Nucleus speckle. Nucleus matrix.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.