Caveolin-3 Rabbit mAb [ED43]Cat NO.: A12246

Protein names ：CAV3; M-caveolin; Caveolin 3; VIP21;

UniProtID ：P56539

MASS(da) ：17,259

MW(kDa) ：17kDa

Form ：Liquid

Purification ：Affinity-chromatography

Host ：Rabbit

Isotype ： IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with A synthesized peptide derived from human Caveolin-3

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：Human fetal heart lysate.

Function ： May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress (By similarity). Mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae (PubMed:19262564)..

Tissue specificity ：Expressed predominantly in muscle..

Subcellular locationi ：Golgi apparatus membrane,Peripheral membrane protein. Cell membrane,Peripheral membrane protein. Membrane, caveola,Peripheral membrane protein. Cell membrane, sarcolemma.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.