Plectin Rabbit mAb [Q9rE]Cat NO.: A53547

Protein names ：EBS1; EBSO; HD1; Hemidesmosomal protein 1; PCN; pleC; PLEC1 ;Plectin 1; Plectin 6; Plectin; PLTN

UniProtID ：Q15149

MASS(da) ：531,791

MW(kDa) ：531kDa

Form ：Liquid

Purification ：Affinity-chromatography

Host ：Rabbit

Isotype ： IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with A synthesized peptide derived from human Plectin

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：Jurkat cell lysate.

Function ： Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the filaments network, but also in the regulation of their dynamics. Structural component of muscle. Isoform 9 plays a major role in the maintenance of myofiber integrity..

Tissue specificity ：Widely expressed with highest levels in muscle, heart, placenta and spinal cord.

Subcellular locationi ：Cytoplasm, cytoskeleton. Cell junction, hemidesmosome.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.