CD11c Rabbit mAb [bU95]Cat NO.: A40761

Protein names ：p150/95 integrin alpha chain; Leu M5; SLEB6; ITGAX; CD11c; p150;Myeloid membrane antigen alpha subunit; Leukocyte surface antigen p150 95 alpha subunit; Integrin alpha-X;

UniProtID ：P20702

MASS(da) ：127,829

MW(kDa) ：128kDa

Form ：Liquid

Purification ：Affinity-chromatography

Host ：Rabbit

Isotype ： IgG

sensitivity ：Endogenous

Reactivity ：Human

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100
• 免疫荧光(ICC/IF)1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with A synthesized peptide derived from human CD11c

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：THP-1 cell lysate treated with TPA.

Function ： Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.

Tissue specificity ：Predominantly expressed in monocytes and granulocytes.

Subcellular locationi ：Membrane,Single-pass type I membrane protein.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.