BPI Rabbit mAb [vJfH]Cat NO.: A65799

Protein names ：rBPI; BPIFD1; CAP 57; BPI; Bactericidal permeability-increasing protein;

UniProtID ：P17213

MASS(da) ：53,900

MW(kDa) ：54kDa

Form ：Liquid

Purification ：Affinity-chromatography

Host ：Rabbit

Isotype ： IgG

sensitivity ：Endogenous

Reactivity ：Human

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫荧光(ICC/IF)1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with A synthesized peptide derived from human BPI

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ：THP1 lysate.

Function ： The cytotoxic action of BPI is limited to many species of Gram-negative bacteria,this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa..

Tissue specificity ：Restricted to cells of the myeloid series.

Subcellular locationi ：Secreted. Cytoplasmic granule membrane.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.