Aquaporin 2 Rabbit mAb [VZVN]Cat NO.: A55550

Protein names ：AQP2,AQP2_HUMAN,Aquaporin-2

UniProtID ：P41181

MASS(da) ：28,837

MW(kDa) ：28KD kDa

Form ：Liquid

Purification ：Protein A purification

Host ：Rabbit

Isotype ：IgG

sensitivity ：Endogenous

Reactivity ：Human,Mouse,Rat

• ApplicationDilution
• 免疫印迹(WB)1:1000-2000
• 免疫组化(IHC)1:100
• The optimal dilutions should be determined by the end user

Specificity ：Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human Aquaporin 2

Storage ：Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected ： Human fetal kidney

Function ： Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient (PubMed:8140421, PubMed:7524315, PubMed:7510718, PubMed:15509592). Plays an essential role in renal water homeostasis (PubMed:8140421, PubMed:7524315, PubMed:15509592)..

Tissue specificity ：Expressed in collecting tubules in kidney medulla (at protein level) (PubMed:7510718). Detected in kidney (PubMed:7510718)..

Subcellular locationi ：Apical cell membrane,Multi-pass membrane protein. Basolateral cell membrane,Multi-pass membrane protein. Cell membrane,Multi-pass membrane protein. Cytoplasmic vesicle membrane,Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane,Multi-pass membrane protein.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.