* 产品详情- */>
Western blot(SDS PAGE) analysis of extracts from HepG2 cells.Using IER3IP1Rabbit mAb [2592] at dilution of 1:1000 incubated at 4℃ over night.
Protein names :IER3IP1,HSPC039,IR3IP_HUMAN,Immediate early response 3-interacting protein 1
UniProtID :Q9Y5U9
MASS(da) :8,969
MW(kDa) :11 kDa
Form :Liquid
Purification :Protein A purification
Host :Rabbit
Isotype :IgG
sensitivity :Endogenous
Reactivity :Human
Specificity :Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human IER3IP1
Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.
WB Positive detected :HepG2 cells
Function : Regulator of endoplasmic reticulum secretion that acts as a key determinant of brain size (PubMed:33122427). Required for secretion of extracellular matrix proteins (PubMed:33122427). Required for correct brain development by depositing sufficient extracellular matrix proteins for tissue integrity and the proliferation of neural progenitors (PubMed:33122427). Acts as a regulator of the unfolded protein response (UPR) (By similarity)..
Tissue specificity :Highest levels in heart, skeletal muscle, and kidney..
Subcellular locationi :Endoplasmic reticulum membrane,Multi-pass membrane protein.
IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.