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IER3IP1 Rabbit mAb [2592]Cat NO.: A14373

Western blot(SDS PAGE) analysis of extracts from HepG2 cells.Using IER3IP1Rabbit mAb [2592] at dilution of 1:1000 incubated at 4℃ over night.

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Product information

Protein names :IER3IP1,HSPC039,IR3IP_HUMAN,Immediate early response 3-interacting protein 1

UniProtID :Q9Y5U9

MASS(da) :8,969

MW(kDa) :11 kDa

Form :Liquid

Purification :Protein A purification

Host :Rabbit

Isotype :IgG

sensitivity :Endogenous

Reactivity :Human

  • ApplicationDilution
  • 免疫印迹(WB)1:1000-2000
  • 免疫组化(IHC)1:100
  • 免疫荧光(ICC/IF) 1:100
  • The optimal dilutions should be determined by the end user

Specificity :Antibody is produced by immunizing animals with a synthetic peptide at the sequence of human IER3IP1

Storage :Antibody store in 10 mM PBS, 0.5mg/ml BSA, 50% glycerol. Shipped at 4°C. Store at-20°C or -80°C. Products are valid for one natural year of receipt.Avoid repeated freeze / thaw cycles.

WB Positive detected :HepG2 cells

Function : Regulator of endoplasmic reticulum secretion that acts as a key determinant of brain size (PubMed:33122427). Required for secretion of extracellular matrix proteins (PubMed:33122427). Required for correct brain development by depositing sufficient extracellular matrix proteins for tissue integrity and the proliferation of neural progenitors (PubMed:33122427). Acts as a regulator of the unfolded protein response (UPR) (By similarity)..

Tissue specificity :Highest levels in heart, skeletal muscle, and kidney..

Subcellular locationi :Endoplasmic reticulum membrane,Multi-pass membrane protein.

IMPORTANT: For western blots, incubate membrane with diluted primary antibody in 1% w/v BSA, 1X TBST at 4°C overnight.